Monte Carlo Tree Diffusion with Multiple Experts for Protein Design (MCTD-ME)
Preprint (arXiv 2025) · In submission
with Xuefeng Liu, Songhao Jiang, Xiao Luo, Xiaotian Duan, Mengdi Wang, Tobin R. Sosnick, Jinbo Xu, Rick L. Stevens
Reframes reverse diffusion as Monte Carlo Tree Search with multiple proposal experts; pLDDT-guided masking and uncertainty-aware selection improve protein design quality and efficiency.